Roxithromycin
0.00৳
Product Name: Roxithromycin, Roxithromicin Powder API, Raw Material BP, EP, USP
Synonyms: Roxithromycine; Roxithromycinum
CAS Number: 80214-83-1
Characteristics: White or almost white crystalline powder
Assay: 96.0% ~ 102.0% Roxithromycin
Formula: C41H76N2O15
Structure Formula:
Package information: 25Kg/Fiber Drum, Cardboard Drum, Paper Drum
Roxithromycin
Product Name: Roxithromycin, Roxithromicin Powder API, Raw Material BP, EP, USP
Synonyms: Roxithromycine; Roxithromycinum
CAS Number: 80214-83-1
Characteristics: White or almost white crystalline powder
Assay: 96.0% ~ 102.0% Roxithromycin
Formula: C41H76N2O15
Structure Formula:
Package information: 25Kg/Fiber Drum, Cardboard Drum, Paper Drum
KEY Words: Roxithromycin, Roxithromicin Powder API, Raw Material BP, EP, USP
Description and Usage:
Roxithromycin is an antibiotic. It has an immunomodulatory effect. Roxithromycin is known to be a wide antibacterial spectrum against oral pathogens.
Roxithromycin can also increase neutrophil apoptosis. It is semisynthetic Erythromycin derivative. Antibacterial.
While Roxithromycin is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections. It is a semi-synthetic macrolide anti-biotic (similar antimicrobial spectrum as erythromycin).
Roxithromycin prevents bacteria from growing, by interfering with their proteinynthesis.
Roxithromycin is very effective against certain gram-negative bacteria.
Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. It can treat respiratory tract, urinary and soft tissue infections. It is not available in the United States, but is available in Australia.
Roxithromycin belongs to a group of medicines called macrolide antibiotics.
It is used for the treatment of the following infections:
- Respiratory infections from both upper and lower airways, such as otitis, sinusitis, pharyngitis, tonsillitis, bronchitis and pneumonia..
- Skin and soft tissue infections.
- Urinary tract infections.
As a professional China Roxithromycin Powder API, Raw Material BP, EP, USP supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Roxithromycin Powder API, Raw Material BP, EP, USP from China in China for almost 10 years.
Caution: Do not use roxithromycin there is following conditions If you are allergic (hypersensitive) to roxithromycin.
Allergy symptoms may include:
- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).
Nor you should take this medicine:
If you are being treated with rye ergot alkaloids.
COA of Roxithromycin :
Testing Item | Standard | Result |
Appearance Roxithromycin |
White or almost white crystalline powder | Complies |
Solubility: | Roxithromycin is very slightly soluble in water, freely soluble in acetone, in alcohol and in methylene chloride. It is slightly soluble in dilute hydrochloric acid | Positive |
Identification 1: | IR: Conforms to the Roxithromycin CRS Spectrum | Complies |
Identification 2: Roxithromycin |
HPLC: Similar inretention time and size to the principal peak of reference solution (a) | Complies |
Appearance of solution: | Clear and colorless | Clear and colorless |
Specific Optical Rotation | -93° ~ -96° | -95° |
Impurity G | ≤ 1.0% | 0.19% |
Impurity A,B,C,D,E,F,H,I,J | ≤ 0.5% | 0.32% |
Total Impurities | ≤ 3.0% | 1.9% |
Heavy Metal | ≤ 10ppm | 10ppm |
Water | ≤ 3.0% | 1.9% |
Sulphated Ash | ≤ 0.1% | 0.01% |
Residual on Ignition | ≤ 0.1% | 0.05% |
Methanol | ≤ 3000ppm | 589ppm |
Acetone | ≤ 5000ppm | 47ppm |
Methylene Chloride | ≤ 600ppm | Not Detected |
Assay Roxithromycin | 96.0% ~ 102.0% | 98.9% |
Others related products
Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid
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