Ciprofloxacin HCL
0.00৳
Ciprofloxacin Base CAS 85721-33-1, Ciprofloxacin Lactate CAS 97867-33-9, Ciprofloxacin Hydrochloride or Hcl CAS 86483-48-9, Ciprofloxacin HCL
| Product Name: | Ciprofloxacin Base API, Raw Material | Ciprofloxacin Lactate API, Raw Material | Ciprofloxacin Hydrochloride API, Raw Material |
| Synonyms: | Cipfloxacine,
Ciprofloxacini |
Ciprofloxacini Lactate | Ciprofloxacin Hcl,
Ciprofloxacini hydrochloridum |
| CAS: | 85721-33-1 | 97867-33-9 | 86483-48-9
or 86393-32-0 |
| Appearance: | White crystalline powder | White powder or crystalline powder | A pale yellow, crystalline powder, soluble in water |
| Assay: | 98.0%-102.0% | 98.5% Min | 98% ~ 102% |
| Formula: | C17H18FN3O3 | C20H22FN3O5 | C17H18FN3O3,HCl,H2O |
| Structure: | |||
| Package: | 25Kg/Fiber Drum, Cardboard Drum, Paper Drum | ||
Ciprofloxacin Base CAS 85721-33-1, Ciprofloxacin Lactate CAS 97867-33-9, Ciprofloxacin Hydrochloride or Hcl CAS 86483-48-9, Ciprofloxacin HCL
| Product Name: | Ciprofloxacin Base API, Raw Material | Ciprofloxacin Lactate API, Raw Material | Ciprofloxacin Hydrochloride API, Raw Material |
| Synonyms: | Cipfloxacine,
Ciprofloxacini |
Ciprofloxacini Lactate | Ciprofloxacin Hcl,
Ciprofloxacini hydrochloridum |
| CAS: | 85721-33-1 | 97867-33-9 | 86483-48-9
or 86393-32-0 |
| Appearance: | White crystalline powder | White powder or crystalline powder | A pale yellow, crystalline powder, soluble in water |
| Assay: | 98.0%-102.0% | 98.5% Min | 98% ~ 102% |
| Formula: | C17H18FN3O3 | C20H22FN3O5 | C17H18FN3O3,HCl,H2O |
| Structure: | |||
| Package: | 25Kg/Fiber Drum, Cardboard Drum, Paper Drum | ||
Description:
Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride are both slats of Ciprofloxacin. They are all broad-spectrum antimicrobial carboxyfluoroquinolines. They belong to fluoroquinolone class. Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride have bactericidal ability because they will inhibit enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. There 2 enzymes needed in many bacterial DNA processes, like replication, transcription, repair, strand supercoiling repair, and recombination.
Ciprofloxacin Lactate, Ciprofloxacin Hcl are applied to treat many bacterial-caused infections such as lung or respiratory tract infections, eye infection, bladder and kidney infections, reproductive tract infections, skin and soft tissue infections and bone and joint infections.
Till now, there is still no cross-resistance between ciprofloxacin and other classes of antimicrobials known to us. We should note that Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride have 100 times higher affinity for bacterial DNA gyrase than for mammalian.
As a professional China Cipfloxacin Base, Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride Raw Material API supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Cipfloxacin Base, Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride Raw Material API from China for almost 10 years.
Mechanism of Action:
The way of action of Cipfloxacin Base, Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride is different from that of other antimicrobial agents like beta-lactams, macrolides, tetracyclines, or aminoglycosides; That is to say, organisms which are resistant to these drugs are still ciprofloxacin. Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride will still work to them.
Absorption of Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride:
Ciprofloxacin will be absorbed from the gastrointestinal tract after oral administration very quickly. The absolute bioavailability is approximately seventy percents with no substantial loss by first pass metabolism.
COA—Ciprofloxacin Base
| Name of Product | Ciprofloxacin base | |
| Testing Item | Standard | Result |
| Appearance
Ciprofloxacin base |
White crystalline powder |
White Crystalline Powder |
| Clarity of solution
Ciprofloxacin base |
Meet the requirements | Meets the requirements |
| Loss on drying | ≤1.0% | 0.2% |
| Residue on ignition | ≤0.2% | 0.12% |
| Heavy metals | ≤0.002% | ≤0.002% |
| Sulfate
Chloride |
≤0.04%
≤0.04% |
＜0.04%
<0.02% |
| Fluoroquinolonic acid | Meet the requirements | Meets the requirements |
| Ciprofloxacin ethylenediamine anlog | ≤0.2% | 0.05% |
| Any other individual impurity | ≤0.2% | 0.03% |
| Total impurities | ≤0.5% | 0.14% |
| Assay (on the anhydrous basis) | 98.0%-102.0%
Ciprofloxacin Base |
100.9% |
COA—Ciprofloxacin Lactate
| Name of Product | Ciprofloxacin Lactate | |
| Testing Item | Standard | Result |
| Appearance
Ciprofloxacin Lactate |
Almost white or light yellow crystalline powder; Odorless and bitter, hygroscopicity | Complies |
| Identification A | Bismuth potassium Iodide solution test: Solution shows brownish red. | Complies |
| Identification B
Ciprofloxacin Lactate |
UV: Absorption max at 277nm | Complies |
| Identification C | IR: Conforms to the reference spectrum | Complies |
| Identification D
Ciprofloxacin Lactate |
Lactate Test: Positive | Complies |
| pH | 4.5 ~ 5.5 | 4.9 |
| Clarity of solution | Clear | Clear |
| Color of solution | Absorption at 430nm ≤0.05 | 0.03 |
| Fluoride | ≥ 4.2% | 4.5% |
| Related Substances | Individual Impurity ≤0.5%
Total Impurities ≤1.0% |
< 0.5%
< 1.0% |
| Loss on drying (60 °C) | ≤ 6.5% | 4.4% |
| Residual on Ignition | ≤ 0.1% | 0.08% |
| Heavy Metal | ≤ 20ppm | < 20ppm |
| Assay (Ciprofloxacin Lactate) | ≥ 98.5% on dried basis | 98.9% |
COA—Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl)
| Name of Product | Ciprofloxacin Hcl or Ciprofloxacin Hydrochloride | |
| Testing Item | Standard | Result |
| Characters
Ciprofloxacin Hcl |
Faintly yellowish to light yellow crystals | Complies |
| Identification A | IR Spectrum of sample complies with the reference standard | Complies |
| Identification B
Ciprofloxacin Hcl |
HPLC: The retention time of the major peak of the sample solution corresponds to the one of standard solution, as obtained in the assay | Complies |
| Identification C | Show reaction of chlorides. | Complies |
| pH | 3.0 ~ 4.5 | 3.7 |
| Water | 4.7% ~ 6.7% | 5.3% |
| Residue on ignition | ≤ 0.1% | 0.05% |
| Heavy metals | ≤ 20ppm Ciprofloxacin Hydrochloride | < 20ppm |
| sulfate | ≤ 0.04% | < 0.04% |
| Fluoroquinolonic acid | ≤ 0.2% | Complies |
| Ciprofloxacin ethylenediamine | ≤ 0.2% | 0.04% |
| Any other individual impurity | ≤ 0.2% | 0.05% |
| Total impurities | ≤ 0.5% | 0.18% |
| Ethanol | ≤ 4000ppm | 426ppm |
| Isoamyl Alcohol | ≤ 4000ppm | Not detected |
| Assay (on the anhydrous basis) | 98.0% ~ 102.0%
Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl) |
99.4% |
Related products
Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid
Supplier in Bangladesh- Elite Scientific & Meditech Co.
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